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KMID : 0360220090500111698
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Journal of the Korean Ophthalmological Society
2009 Volume.50 No. 11 p.1698 ~ p.1704
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Anticholinesterase Treatment for Patients With Paralytic Strabismus Following a Viper Bite
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Lee Jung-Ho
Ahn Sung-Min
Jung Bo-Young
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Abstract
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Purpose: To describe the therapeutic effect of anticholinesterase treatment for patients with paralytic strabismus and blepharoptosis following a viper bite
Methods: A prospective non-comparative interventional case series study was designed including 6 patients with ophthalmic complications such as paralytic strabismus and blepharoptosis following a viper bite. Anticholinesterase (pyridostigmine) 60 mg was administered to patients 3 times a day in additional to conservative treatment including antivenom, antibiotics and tetanus toxoid. Patients underwent a measurement of deviation, diplopia test and MRD 1. Subjective evaluation of the diplopia symptoms was performed daily after treatment.
Results: Subjective diplopia was relieved in 2 out of the 6 patients on the first day and in the other 4 patients on the second day. The angle of deviation decreased approximately 37% on the first day and ocular position became orthophoric on the third day in all patients. The blepharoptosis was completely resolved in 4 patients on the first day. No complication following anticholinesterase treatment was noticed.
Conclusions: Treatment using anticholinesterase for patients suffering from diplopia and blepharoptosis following a viper bite is an effective and safe treatment.
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KEYWORD
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Anticholinesterase, Blepharoptosis, Paralytic strabismus, Snake bite
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